Aging changes of the optic nerve head in relation to open angle glaucoma

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Aging changes of the optic nerve head in relation to open angle glaucoma.

AIMS To determine the age related changes in optic nerve head structure in a group of normal subjects and assess the significance of any changes in relation to those found in open angle glaucoma. METHODS A group of 88 white volunteers and friends and spouses of patients with a normal visual field and normal intraocular pressure was studied. Two different imaging and measurement devices were u...

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Pit-like changes of the optic nerve head in open-angle glaucoma.

Six patients with open-angle glaucoma and acquired pit-like changes in the optic nerve head are presented. In 1 patient evolution of the pit-like defect is documented. In all 6 patients progression of associated visual field deficits is described. It is suggested that such pit-like changes in selected patients with glaucoma may not represent congenital lesions but rather local, progressive nerv...

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Optic Nerve Head Blood Flow Changes Induced by Ripasudil Added to Prostaglandin Analogues in Primary Open Angle Glaucoma

Purpose: To evaluate the effect of topical ripasudil, a Rho-associated-kinase inhibitor, added to prostaglandin analogue eye drops on optic nerve head (ONH) blood flow in patients with primary open angle glaucoma (POAG). Subjects and Methods: Subjects comprised 12 eyes from 12 patients with POAG who had been using a topical prostaglandin analogue for more than 3 months. ONH blood flow, intraocu...

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Gene Expression Profiling of the Optic Nerve Head of Patients with Primary Open-Angle Glaucoma

Background. The pressure-induced axonal injury of the vulnerable ONH has led many researchers to view glaucoma from the perspective of the genetic basis of the angle of the ONH. However, genetic studies on POAG from this perspective are limited. Methods. Microarray dataset GSE45570 of the ONH of healthy individuals and POAG patients were downloaded from the Gene Expression Omnibus. After screen...

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4137 Implication of intraocular pressure regulation on optic nerve head damage in open angle glaucoma

AGE AND GENDER DIF’FRRRNCIZS IN OPTIC DISC ARR.4, CUF’ AREAANDVERTlCALCW-TO-DI:SCRATIO?THEROlTERDAM STUDY. RAMRAlTAN RSJZ, GA DE WRUYNE’s, M. VAN RJZESv, HOFMAN A.‘, and DE JONG P.T.Q.M.’ Departments of ‘Ophthalmology and aBpidemiology & Biostatistics. Erasmus University Medical School, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. m To investigate cross-sectionally the association of age ...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1997

ISSN: 0007-1161

DOI: 10.1136/bjo.81.10.840